Master learning library

Statistical concepts

Evergreen modules organized around questions investigators need to answer.

Thinking Like an Investigator · 15 minutes

Measurement and Representation

Does numeric coding make a variable continuous?

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Samples and Populations · 16 minutes

Sampling Variability

Why does an estimate change when the population stays fixed?

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Samples and Populations · 17 minutes

Confidence Intervals

What does 95% confidence look like over repeated samples?

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Samples and Populations · 18 minutes

Survey Weights and Clustering

Who gets represented, and how much independent information is present?

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Evidence · 18 minutes

Hypothesis Testing as Evidence

What does a p-value measure, and what does it not measure?

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Relationships · 13 minutes

Categorical Denominators

Among whom is the percentage being calculated?

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Relationships · 17 minutes

Chi-Square as Evidence of Association

How far are observed counts from independence?

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Relationships · 14 minutes

Fisher's Exact Test

What evidence can a small, sparse 2×2 table provide?

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Relationships · 15 minutes

Effect Magnitude Before Significance

How large is the difference in proportions?

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Relationships · 16 minutes

Choosing a Categorical Effect Measure

Should the contrast be absolute, relative-risk, or odds based?

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Evidence · 15 minutes

Statistical Significance vs Policy Importance

Is an association detectable, important, or both?

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Causal Reasoning · 15 minutes

Association vs Causation

What claim does the study design support?

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Causal Reasoning · 17 minutes

Variable Roles

What job does a third variable perform in the analytical argument?

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Causal Reasoning · 18 minutes

DAG Reasoning for Adjustment

Which path are you trying to block without opening another?

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Causal Reasoning · 18 minutes

Confounding and Adjustment

How can different group composition distort a crude comparison?

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Regression · 15 minutes

Probability, Odds, and Log-Odds

How can the same chance be expressed on three different scales?

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Regression · 16 minutes

The Logistic Curve

How can a linear predictor produce probabilities between zero and one?

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Regression · 18 minutes

Introducing Multivariable Logistic Regression

How does one model relate a binary outcome to several explanatory variables?

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Regression · 16 minutes

An Odds Ratio Is Not a Risk Ratio

Why does an odds ratio depend on baseline risk when translated to probability?

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Regression · 17 minutes

Predicted Probabilities

What probability does the fitted model imply for a defined profile or population?

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Regression · 16 minutes

Same-Sample Adjustment

Did the coefficient change because of adjustment or because the sample changed?

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Regression · 19 minutes

Logistic Model Assessment and Selection

Does a candidate model fit adequately and answer the intended question?

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Regression · 14 minutes

Match the Question to the Method

What quantity does the research question require?

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Regression · 15 minutes

The Two-Group t-Test as Regression

How can a two-group mean difference be written as a model?

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Regression · 15 minutes

Correlation and the Standardized Slope

What does a one-predictor slope add to correlation?

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Regression · 18 minutes

Linear Regression as a Model

What does OLS estimate?

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Regression · 16 minutes

Holding Other Variables Constant

What does holding constant mean?

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Regression · 15 minutes

Residuals

What does a residual reveal?

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Regression · 15 minutes

Linearity of the Conditional Mean

Is a straight-line mean relationship plausible?

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Regression · 15 minutes

Heteroskedasticity

Does outcome variability change across fitted values?

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Regression · 15 minutes

Influential Observations

Does one observation have disproportionate influence?

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Regression · 15 minutes

Collinearity

Can the data distinguish the included predictors?

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Regression · 16 minutes

Functional Form

How should a predictor enter the model?

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Regression · 15 minutes

Raw and Log Outcome Scales

What does the outcome scale mean?

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Regression · 16 minutes

Sensitivity Analysis

Would a reasonable alternative change the conclusion?

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Evidence · 15 minutes

Specification Searching

When does model comparison become specification searching?

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Regression · 18 minutes

Effect Heterogeneity and Interaction

Does an association differ across groups?

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Evidence · 17 minutes

Investigator Defense

Can you defend the analysis as an investigator?

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Relationships · 14 minutes

Reading a Distribution

What can shape reveal before any test is run?

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Relationships · 14 minutes

Shape Before Correlation

What relationship can a single correlation coefficient hide?

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Relationships · 16 minutes

Pearson and Spearman Correlation

Are we measuring a linear relationship or a monotonic ordering?

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Relationships · 14 minutes

Mean, Median, and Extreme Values

When does the mean stop describing a typical observation?

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Relationships · 13 minutes

Independent or Paired?

Which observations belong together?

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Relationships · 16 minutes

Choosing a Two-Group Comparison

Are you comparing means, paired changes, or relative positions?

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Relationships · 17 minutes

Comparing Two Means

How large and how uncertain is the difference in means?

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Relationships · 13 minutes

Comparing Two Medians

How far apart are the middle values of two populations?

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Relationships · 18 minutes

Comparing Groups with Ranks

What changes when we replace observed values with their ranks?

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Relationships · 16 minutes

ANOVA as a Comparison of Variation

Are group means separated relative to variation within groups?

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